You can add this script as a cron job to remove the files without rebooting
#!/bin/sh # Clean file and dirs more than 3 days old in /tmp nightly /usr/bin/find /tmp -type f -atime +2 -mtime +2 |xargs /bin/rm -f && /usr/bin/find /tmp -type d -mtime +2 -exec /bin/rm -rf '{}' \; && /usr/bin/find /tmp -type l -ctime +2 |xargs /bin/rm -f && /usr/bin/find -L /tmp -mtime +2 -print -exec rm -f {} \;
save the contents above to a file chmod 775 the file and create a cron entry to run it