I think you miss one set in the configuration of apache with mono. I strongly suggest you to check this guide is for Ubuntu. I tried and it works fine with xsp and apache. I test some examples and work fine for everything except WCF (svc). Apparently, that support it still with a lot of problems in mono 2.10.
http://www.bgsoftfactory.net/run-asp-net-mvc-4-with-mysql-on-linux/
I think the problem could be that the virtual host is not active. But, that is a simple hunch.